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Among the mutants with a defect in LCA-induced biofilm, the most-represented functional category was genes related to LPS biosynthesis (21 unique insertions across 9 genes), followed by flagellar genes (17 unique insertions across 13 genes) (Fig
The discontinuation profile proves more favorable than retinoids showing rapid rebound and high dependency, while similar to vitamin C and niacinamide demonstrating moderate benefit retention and low dependency patterns
The procedure is quick, minimally invasive, and requires no downtime, with results typically visible within a few weeks
The synthesis of the probe followed the route shown in Scheme S1, and the compound was characterized using nuclear magnetic resonance (1H/13C NMR) and high-resolution mass spectrometry (ESI-HRMS) Fig