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The overall result is a progressive deficiency that worsens as the condition develops

Hashimoto, S., Matsuba, Y., Takahashi, M., Kamano, N., Watamura, N., Sasaguri, H., Takado, Y., Yoshihara, Y., Saito, T., & Saido, T

This allows ULK1 to assemble with ATG13, FIP200, and other components [91], forming an activation complex that targets the MAMs region [92, 93]

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