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In cases of severe deficiency, a course of injections may be given over several weeks before transitioning to maintenance treatment

In the late follicular phase, with the E2 level continuing to rise, it produces a positive feedback effect on the hypothalamus and pituitary, which causes the LH level to rise sharply, and ovulation occurs

Suprachiasmatic nucleus-mediated glucose entry into the arcuate nucleus determines the daily rhythm in blood glycemia

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PMID: 17233798 DOI: 10.1111/j.1464-410X.2006.06742.x Barrett DM (1981): The effect of oral bethanechol chloride on voiding in female patients with excessive residual urine: a randomized double-blind study