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reported that in early stage of menopause (particularly less than five years after menopause), the proinflammatory cytokines levels in the serum were increased and return to the normal levels in the late stage, with values parallel to pre menopause phase [26]

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Additionally, Hayes and Swift [52] emphasized that the conformational flexibility of HS is key to regulating mineral interactions and nutrient availability

doi: 10.1371/journal.pgen.1009200 224 NeilR

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