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Compared with traditional meta-analysis using linear mixed effect models, MR-BRT relaxes the assumption of a log(linear) relationship between exposure and risk, incorporates between-study heterogeneity into the uncertainty of risk estimates, handles estimates reported across different exposure categories, automatically identifies and trims outliers, and systematically tests and adjusts for bias due to study designs and characteristics

The state has since kept the 15 percent excise tax on producers but shifted to a 15 percent excise tax on consumers while exempting cannabis sales from the state sales tax

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Most of the studies focus on the effects of smoking on male and female infertility