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Mechanistically, ginger's active compound, [6]-shogaol, has been identified as a mediator of vasodilation, primarily through its action on calcitonin gene-related peptide (CGRP) pathways and subsequent activation of endothelial nitric oxide synthase

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Silymarin, a promising pharmacological agent for treatment of diseases, Iranian Journal of Basic Medical Sciences (2011) Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review, Phytotherapy Research (2019) Milk thistle, Mount Sinai Milk thistle, Mayo Clinic Milk thistle, National Center for Complementary and Integrative Health Milk thistle, National Library of Medicine (2023) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice

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