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Disease-associated changes in bile acid profiles and links to altered gut microbiota

Diehl FF, Lewis CA, Fiske BP, Vander Heiden MG

To better understand the role of immune mechanisms in the formation of NETs and the processes related to the generation of free radicals during miscarriage, we decided to expand our study by assessing the concentrations of nicotinamide adenine dinucleotide phosphate oxidase 1 (NOX1), which is one of the isoforms of nicotinamide adenine dinucleotide phosphate hydrogen (NADPH), and that of NCF2 (neutrophil cytosolic factor 2, NOXA2), which is an integral protein of the NADPH oxidase (Chocry and Leloup 2020)