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Recent studies have revealed the elevation of SIRT1 in a rat model of status epilepticus, a common neurological emergency which is defined as a prolonged seizure with at least five minutes or multiple seizures with incomplete recovery of consciousness [117] and its neuroprotection is conducted via deacetylation of proliferator-activated receptors and coactivator 1 (PGC-1), an important regulator for mitochondrial biogenesis [118, 119]

Acute cholecystitis: early versus delayed cholecystectomy, a multicenter randomized trial (ACDC study, NCT00447304)

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