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In addition, a large number of anti-tumor drugs were reported to damage DNA, produce AP sites and promote apoptosis, and AP capture efficiently enhanced their cytotoxicity [32]

Some of the negative effects of high homocysteine levels are modulated by the PON1 genotype.[ref] BLMH and BPHL are additional enzymes that can also metabolize homocysteine-thiolactone.[ref] Higher levels of homocysteine-thiolactone are also found in chronic inflammatory conditions, such as rheumatoid arthritis, inflammatory eye disease, and AMD.[ref][ref][ref] Lets take a look at why high homocysteine levels cause problems in the body, and then well look at genetic variants in the above cycles that can affect homocysteine levels when combined with dietary choices

Working as expected with little side effects

In the histopathological evaluation of the liver sections, the control rats had a typical central vein and hepatocyte arrangement as well as a normal structure with no histological abnormalities