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PubMed Central , World Journal of Gastroenterology : WJG , vol

Oxidative stress can cause abnormal expression of various inflammatory markers, resulting in mitochondrial dysfunction and aberrant cellular energy metabolism, further increasing the joint burden and exacerbating joint damage [6, 7]

However, clinical research commonly tests doses ranging from 250 to 600 milligrams per day, with the most effective results often observed at 500600 milligrams daily taken consistently for at least one to two months

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6c), indicating that H 2 O 2 catalyzed by NP4 not only disrupted the redox balance within tumor cells but also diffused outside the cells, leading to more cascading reactions