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Additionally, the RPE physically interacts with the outer retinal blood supply, known as the choroid, forming a structure known as the outer bloodretinal barrier (BRB)

These obstructions made of keratin, cellular debris, granulation tissue, and/or fibrosis can increase stress, contribute to progression of disease, result in lid tenderness, inflammation, recurrent eyelid infections (styes, hordeola, chalazia, cellulitis), and other symptoms of ocular irritation, and can exist simultaneously with traditional MGD

Schauss AG, Vrtesi A, Endres JR, et al

Common Protocol: MK-677: 12.525 mg daily, oral, taken at night BPC-157: 250500 mcg daily, subcutaneous Cycle: 812 weeks for MK-677