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The peptide's combined sleep-promoting and analgesic properties may be particularly relevant for pain conditions where sleep disruption exacerbates pain perception in a vicious cycle

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Lee told Undark that he learned about peptides in 2016, while attending a conference

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In severe acute pancreatitis (SAP), inflammatory factors promote the expression of matrix metalloproteinases (MMPs) and heparinases, which degrade syndecan-1 (SDC-1) and HS, while oxidative stress disrupts HA-CD44 binding, leading to increased capillary leakage and neutrophil adhesion