Translating a 15 mg/kg murine dose directly to humans underscores a severe translational gap in the source paper
Third-party testing provides independent verification of compound quality that researchers need to maintain experimental validity
[DOI] [PubMed] [Google Scholar] 35.Mzsik G
Previous panelists included university experts in dermatology, anesthesiology, pediatrics and pharmacy compounding
Walking Recovery Index (WRI) As described previously [13], to objectively measure gait recovery, recordings were carried out using a fixed digital camera placed under the animals (Olympus mju 300 digital, Olympus Optical Co., Ltd., Hachioji, Tokyo, Japan), located 25 cm below and 12 cm to the side of a 100 cm long closed transparent plexiglass tunnel, and measurements and the gait recovery index were calculated, expressed as a coefficient of the length of the footprints with which the animal rests on the ground in certain phases of walking, according to the following Equation (1): where NPL stands for the non-injured animal footprint length, while EPL stands for the experimental animal footprint length, expressed in millimeters