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Regulatory watch Last reviewed Jul 12, 2026 Next review Jul 24, 2026 Evidence snapshot Human trial record: a Phase 1 safety and pharmacokinetics registry entry has no posted efficacy result

Previous colectomy with an end-ileostomy or with a continent ileal pouch does not preclude pregnancy, and for some women, vaginal delivery is still an option

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Two recent meta-analyses that pooled data from patients with end-stage renal disease found no benefit of B-vitamin supplementation on stroke outcomes (34, 35)

At least 75 genetic variants are associated with an increased risk of Alzheimer's