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FOXO4 had already been studied and found to be associated with aging Hmmmmmm seems like were onto something here
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For this aim, we collected serum and villous tissue samples from patients with unexplained miscarriage and their matched healthy control group, constructed a LiCl-exposed pregnant mouse model, and used LiCl-exposed human trophoblast Swan 71 cells
Similarly, a recent cross-sectional study in healthy nurses found that NS workers had significantly lower plasma melatonin levels compared to DS workers, alongside trends toward altered leptin, ghrelin, and metabolic parameters, supporting the role of circadian disruption in predisposing to metabolic syndrome, which is a risk factor for BC development 175
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