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These polymorphisms are unrelated to cobalamin metabolism and the elevated MMA levels do not, by themselves, indicate a B12 deficiency (Molloy, 2016)

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Conservative treatment includes physical therapy, medications appropriate to the diagnosis, and other non-invasive interventions

Preclinical Studies Early preclinical studies in rodent obesity models demonstrated that AOD9604 administration reduced body weight and fat mass without affecting food intake, indicating a direct metabolic effect rather than an appetite-suppressing mechanism