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In transgenic mouse models of AD, KD reduced soluble A deposits in the brain by 25% after only 40 days [102]

However, the use of herbal drugs faces several limitations, such as toxicity, difficulty in extraction, low yield, standardization problems, complex dosage regimens, stability issues, and lack of specific targeting

But dehydration worsens nearly every side effect, from nausea to constipation to fatigue

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Profound analysis highlighted the inhibitory effect of PPIs on the PI3K pathway, which specifically targets the PI3K/SREBP-1/SCD1 axis with notable tolerability