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Research models show it delivers Cu ions to copper-dependent enzymes (lysyl oxidase chief among them) that crosslink collagen and elastin fibers, producing denser, more resilient extracellular matrix

Nonetheless, in patients receiving anticoagulants or antiplatelet agents, high-dose EPA formulations warrant enhanced monitoring to mitigate potential additive bleeding risk

Comparing both to semaglutide (Ozempic/Wegovy) Any conversation about retatrutide versus Mounjaro would be incomplete without placing both in the context of semaglutide, the drug that started the GLP-1 weight loss revolution

Diabetes Res Clin Pract 1991;14:191-5

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