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J Biol Chem 272(47):2939929402 Wilkinson B, Gilbert HF (2004) Protein disulfide isomerase

Aggregation happens when peptide molecules stick together, forming larger complexes that may precipitate from solution or lose biological activity

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Collectively, these results demonstrate that the cytoprotective effects observed in MAPKAPK2-overexpressing vitiligo melanocytes under oxidative stress conditions are specifically dependent on MAPKAPK2