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These results suggest that GHR expression in AgRP neurons is unnecessary for the regulation of energy homeostasis under normal circumstances or for the response to key hormones that rely on AgRP neurons to modulate energy homeostasis

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10.15252/emmm.202114146 12 ChenM.ChoiS.WenT.ChenC.ThapaN.LeeJ

A mechanistic rationale that is coherent and specific, not speculative