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J Endocrinol Metab

GHK-Cu's effectiveness without significant irritation makes it suitable for this challenging area where retinoids often cause problems

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Hepatology 54 , 989998 (2011)

For example, human induced pluripotent stem cell (iPS cell) astrocyte studies indicate that PSEN1 mutations enhance cytokine signaling via disrupted intramembrane proteolysis, lowering the threshold for astrocyte reactivity and predisposing cells to exaggerated inflammatory responses to modest stimuli 79