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doi: 10.1002/cche.10779 189 de Almeida Sousa CruzMAde Barros EliasMCalinaDSharifi-RadJTeodoroAJ

Importantly, high-dose glucocorticoids remain a mainstay of immunosuppressive induction therapy upon solid organ transplantation to prevent acute rejection [8], spurring interest to thoroughly characterize the effects of glucocorticoids on ferroptosis

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The study was conducted from April to December 2015

KPV works through NF-kB inhibition via IkB-alpha stabilization, MAPK suppression, and PepT1-mediated intracellular uptake