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Because bone and joint damage occur later in the course of the disease, X-rays may not be very useful in detecting RA in the early stages, although soft tissue swelling around a joint can be seen on a regular X-ray

doi: 10.3978/j.issn.2072-1439.2012.09.01

Metabolic-dysfunction and obesity-pathway preclinical investigations

Reported side effects The side effects reported in trials and research protocols tend to be mild and transient: Common: Injection site reactions: redness, swelling, mild irritation at the injection location Headache: reported in some subjects, typically mild and temporary Mild gastrointestinal discomfort: occasional reports of nausea or upset stomach Less common: Temporary dizziness Slight increases in heart rate Minor liver enzyme elevations in some subjects These effects, when they occur, generally resolve without intervention and don't require discontinuation

For research integrity, we recommend discarding it and starting over