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While our in vitro developability assessments were performed on a small cohort of target-specific, high-expression antibodies from each repertoire and requires validation in a larger, more unbiased subset to definitively attribute native pairing to gains in developability, the bioinformatic workflows employedparticularly our clustering-based clonal selection strategiessuggest that the selected antibodies should be representative in sequence and function of the larger target-specific diversity

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Protein and peptide S-nitrosothiols (SNOs) are involved in guanylate cyclase-independent signaling associated with nitric oxide synthase (NOS) activation

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