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(4) Diseases: Chronic kidney disease, severe anemia, hypothyroidism, malignancy and drugs that affect the absorption of B vitamins and FA have been shown to increase Hcy level ( 4 Hcy and thyroid hormones Thyroid hormone (TH) is a major regulator of cellular metabolism and maintains metabolic homeostasis by coordinating networks of carbohydrate, lipid and protein metabolism

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This improves both tensile strength and elasticity , helping tendons adapt to load more efficiently

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[DOI] [PubMed] [Google Scholar] 74.Terzyan SS, Cook PF, Heroux A, Hanigan MH: Structure of 6-diazo-5-oxo-norleucine-bound human gamma-glutamyl transpeptidase 1, a novel mechanism of inactivation