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The presence of an extra X chromosome (Klinefelter syndrome) or an extra Y chromosome, the presence of two X but no Y chromosome in a male, and microdeletions or translocations affecting the X or Y chromosome are examples of chromosomal problems that can disrupt sperm production and overall genital and gonad development, resulting in azoospermia (absence of sperm) and infertility

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Research shows that GHK-Cu can influence over 4,000 human genes, many of which are related to tissue repair and cellular regeneration

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77 In a controlled trial in 262 men with infertility related to poor sperm number, motility, and morphology, a combination of 1 gram of L-carnitine twice daily plus 20 mg CoQ10 three times daily resulted in greater improvement in sperm motility and a higher pregnancy rate than either supplement alone or placebo