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In the SURPASS-2 study, tirzepatide 15 mg resulted in a faster and greater decline in body weight ( 5.5 kg) compared to semaglutide 1.0 mg, more than doubling the proportion of patients achieving at least 10% weight loss (57% vs 24%) [3]

(2024) Protocol for the in vitro reconstruction of site-specifically phosphorylated RNA Pol II to identify the recruitment of novel transcription regulators

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NSAIDs decrease COX activity primarily by competitive inhibition

specifically, the accumulation of a large amount of lipid peroxides and the depletion of GSH have been detected in kainic acid-induced TLE in rats, accompanied by a reduction in the mitochondrial area of hippocampus neuron (Ye et al., 2019)