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The condition is predominantly distinguished by the abnormal and excessive proliferation of keratinocytes in the epidermis, which results in the formation of thickened, scaly plaques on the skin (Pondeljak et al

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Within the Cancer category (p-value dynamical range: 7.03 10 12 to 2.64 10 3 , n = 48) disease annotations with predicted activation included abdominal carcinoma (p = 7.96 10 08 , n = 12), epithelial neoplasm (p = 2.40 10 7 , n = 20), and tumorigenesis of epithelial neoplasm (p = 1.08 10 4 , n = 13)

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