Trehalose attenuates oxidative stress and endoplasmic reticulum stress-mediated apoptosis in IPEC-J2 cells subjected to heat stress
Zhang R, Zhang X, Zhang J, Wu J, Ye Q, Xu R, Ye J, Fang X, Jin L, He J, Yuan W
Effects of an effective concentration of nicotine (N 250 g/ml) in the presence or absence of glutathione (G 14 g/ml) on the metabolism of 14C-testosterone and 14C-4-androstenedione in HGF (Figures 3 & 4) When 14C-testosterone was used as substrate (Figure 3) there was a 2-fold reduction in the production of D (a metabolite of DHT) when compared to controls in response to N with 33% less inhibition when G was added (NG 2,3,4 )
When administered at therapeutic levels, APAP is primarily metabolized via the glucuronidation pathway, producing non-toxic metabolites that the liver and kidneys can further process (Chiew and Isbister 2023)
A study in Japan demonstrated that sericin inhibits tyrosinase activity in silk