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Earlier detection typically leads to less intensive treatments and better survival rates

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The T-cell undergoes clonal expansion and some clones of the newly formed antigen specific sensitized T-cells travel back to the site of antigen exposure

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For protein isolation, cells were washed with cold PBS, collected in lysis buffer using a cell scraper, incubated on ice for 20 min, and centrifuged for 5 min at 500 rpm