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Plasmacytoid dendritic cells produce excessive type I interferons, driving a cascade of immune activation

ATP levels were determined by measuring fluorescence at Ex/Em = 535/587 nm, using a multi-well plate reader (Synergy H1, BioTek Instruments, Inc., Warsaw, Poland)

While BWFI for RUO may not be subject to the same direct patient-use regulations, the principles of purity, sterility, and quality control are highly relevant

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Although these findings appear promising, the utility of intravenous NAC repletion as a therapeutic strategy in PD is greatly limited by invasiveness and inconvenience of intravenous delivery