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The intermediate metabolites of the MVA pathway, specifically isopentenyl pyrophosphate (IPP), farnesyl pyrophosphate (FPP), and geranylgeranyl pyrophosphate (GGPP), can prenylate GTPases, thereby facilitating tumor progression [57]

The amino acid-derived compounds have been shown to intervene in human cell physiology by modulating proliferation, gene expression, energy metabolism and redox state, resulting in the modulation of various central physiological functions

Peters B, Vahlhaus J, Pivovarova-Ramich O

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On one hand, AMPK rapidly regulates enzyme activity through phosphorylation events [68]