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Its mechanism is competitive inhibition within the NNMT catalytic pocket, blocking the methyl transfer from SAM to nicotinamide

Conclusion Considering the promising effects of vitamin B12 in improving disease severity and anxiety of FM patients as well as the absence of any side effects in the studied dosage, we postulate that vitamin B12 has a strong potential to consider, at least, as an adjunctive therapy of FM

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Allergic Reactions: While uncommon, some individuals may experience allergic reactions to the injection, which can include itching, rash, or difficulty breathing