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doi: 10.1042/BJ20081386 65 PKGCJnW

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Common Causes of Cholestasis Disease Clinical clue Diagnostic test Primary biliary cholangitis Primary sclerosing cholangitis Large bile duct obstruction Drug-induced Infiltrative disorder Inflammation-associated Woman Association with ulcerative colitis Jaundice and pain are common Compatible medication or timing History of malignancy, amyloidosis, sarcoidosis Symptoms of underlying inflammatory disorder Antimitochondrial antibody MRCP Ultrasonography, CT, MRCP, ERCP Improvement after agent is withdrawn Ultrasonography, CT, MRI Blood cultures, appropriate antibody tests Abbreviations: CT, computed tomography