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Preclinical and clinical studies have demonstrated its efficacy in reducing body weight both as a monotherapy and in combination with GLP-1 receptor agonists such as semaglutide, highlighting its potential as a next-generation therapeutic agent for obesity and metabolic syndrome management

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To assure this, there is a constant water secretion in the entire GI tract from the duodenum to the distal colon

This reflects the underlying biology of obesity as a chronic condition requiring ongoing management

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