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mBio 3 , (2012)

PMID: 28969876 Curtis LA et al (2001): Acute urinary retention and urinary incontinence

Dramatic improvements in fine lines or scarring often take 3 to 6 months

It is comparatively more efficacious and has a better safety profile than the oral forms of this medicine, although adverse effects such acne, redness, and itching at the application site, inflammation of the throat and nasal passages, headaches and fever have been observed, necessitating the need for observational studies and randomized controlled trials to demonstrate its efficacy and safety

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