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3.4 Evidence Base Neuropathy Trials : RCTs in diabetic neuropathy show 1,5003,000 mcg methylcobalamin daily improves nerve conduction velocities by up to 20% over 12 weeks

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While there is no problem with doing so, and we as medical professionals do actually recommend supplements in specific cases, this may not be the most optimal method for B12

In research, TB-500 has been administered 12 times per week with peak efficacy (8)