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ACKNOWLEDGEMENT The authors declare no conflict of interest relevant to this article

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Gut microbial diversity is significantly lower in patients with SLE with active disease than in non-SLE controls ( Firmicutes decreased compared to the non-SLE controls, while Bacteroidetes increased ( 2.2 Characteristics of gut microbiota in patients with AITD As shown in Table 1 , some studies have proposed compositional modifications and bacterial ecological imbalances arise in the gut microbiota of patients with AITD, indicating that specific bacterial overgrowth and its impact on the gut-thyroid axis may play key roles in the occurrence and progression of AITD ( Table 1 Characteristics of gut microbiota in patients with autoimmune thyroid disease