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Zhou et al., 2002

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For the samples, the severity of the subcutaneous tissue necrosis was assessed by a trained toxicopathologist using a light microscope and scored on a numerical scale, where code 1 reflects no abnormalities and code 5 reflects marked severity: 1 , no abnormalities 2, minimal severity 3, mild severity 4, moderate severity 5, marked severity Results on scores of necrosis are shown in table 24a and table 24b

Deciding on dosage amounts and treatment lengths should be done so in consultation with a trained medical professional