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3 In B12 deficiency, methylmalonic acid (MMA) can accumulate, and it is thought that elevated MMA, alongside elevated homocysteine, contributes to damage of the myelin sheath (which protects nerve cells and speeds up nerve transmission), which can cause irreversible neurological problems

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Pediatr Res 47 : 221224 Laborie S, Lavoie JC, Pineault M, Chessex P 2000 Contribution of multivitamins, air, and light in the generation of peroxides in adult and neonatal parenteral nutrition solutions

So that would be my second option