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Moreover, the authors extended this mechanism to senescent cancer cells and demonstrated that these cells are more efficient than immunogenic cell death to induce immune system protection against tumor relapse

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Therefore, the present review aims to systematically dissect the core molecular mechanisms of ferroptosis, elucidate its specific pathogenic roles in cognitive disorders including AD, PD and DACI as well as provide a comprehensive overview of emerging diagnostic biomarkers and therapeutic strategies targeting this cell death pathway