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Heating intact, uncrushed garlic inactivates the alliinase enzyme and prevents allicin from forming

Elevated levels of oxidative stress have been identified as a detrimental factor contributing to insulin resistance development

doi:10.1186/s12891-017-1571-8 11 Schneider B, Varghis N, Kennedy DJ

In developed countries, excessive calorie intake and frequent consumption of unhealthy foods, associated with a sedentary lifestyle, have caused an increase in the prevalence of obesity, which in turn predisposes to several non-communicable diseases, such as cardiovascular disease, diabetes, hypertension, and chronic kidney disease [9]

However, to realize the full therapeutic potential of RAS in mood disorders, further research is required