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The most well-known active transporter is P-gp, which is located in the syncytiotrophoblast (apical membranematernal side), acting as a pump transport molecule from inside the cell to the extracellular space [85,86] and also functioning as a barrier by protecting the fetus when exposed to xenobiotics

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On-treatment analysis showed weight loss of 22.7% with CagriSema, approaching the efficacy of bariatric surgery