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It was further confirmed that the GBM homing ability of the developed nanoformulation via cellular uptake and internalization study signified its specificity to the U87MG cells, which overexpress the caveolin receptor

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In addition, there are also positive correlations between adolescents and ASVs annotated to the Firmicutes families Lactobacillaceae, Christensenellaceae, Anaerovoracaceae, and Oscillobacteriaceae, and with ASVs annotated to the Bacteroidota Butyricimonas and to the above-mentioned Desulfobacterota D

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Molecular Dynamics (MD) simulations The four model systems (ChaC1-Juglone, ChaC1-Glutathione-Juglone, ChaC1-Juglone-C2-Glutathione-adduct, and ChaC1-Juglone-C3-Glutathione-adduct) were subjected to protein preparation wizard of Maestro available with DESMOND MD simulation package (release 2018) (19) of Schrodinger