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Oxidative distress causes damage to fundamental macromolecules including proteins, lipids, RNA and DNA at a cellular level, which promotes abnormal cell death and inflammation, often culminating in additional oxidative stress at a systemic level

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Ishizawa J, Kojima K, Chachad D, Ruvolo P, Ruvolo V, Jacamo RO, Borthakur G, Mu H, Zeng Z, Matre PR, Allen JE, Sarbassov DD, Neelapu SS, McDonnellT, Miranda R, Wang M, Kwak LW, Kantarjian H, Konopleva M, Davis RE, Andreeff M

DOI: 10.1159/000090495 59

Peptides, exosomes, and stem cells fine-tune that work and make it count for more