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However, prevalence rates among adults younger than age 65 years have tended to converge

It also has depressant effects, causing relaxation, decreasing anxiety, and potentially sedative effects

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59 For this reason, bupropion should be used with extreme caution in patients with a history of seizures, those who have experienced cranial trauma, and those receiving medications known to lower the seizure threshold or those with underlying severe hepatic cirrhosis