Find out why your FIP cat needs B12 In our FIP Advisory and Care group, we routinely advise our members to request B12 injections, and/or B12 supplementation
These convert phosphatidylinositol2-phosphate (PIP2) into phosphatidylinositol-3-phosphate (PIP3) and, by so doing, activates protein kinase B (PKB), the metabolic pathway for glycogen synthesis.1314 In addition to the conversion to phosphatidylinositol-3-phosphate, inositol also acts by activating pyruvate dehydrogenase kinase, isoenzyme 1
With daily B12 shots, you will at least prevent symptoms and nerve damage from getting much worse
In these clinical cases, injections may be given three times a week for several weeks until symptoms begin to subside
Notable recent developments include the first preclinical study demonstrating NNMT inhibition improves cardiac function and reduces fibrosis in a heart failure model (Li et al., 2025), a comprehensive review of NNMT as a therapeutic target for neurodegenerative disorders (Liu et al., 2025), and emerging evidence that NNMT inhibition counteracts tubular senescence and fibrosis in chronic kidney disease
