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Treatment Iron chelation treatment Despite the novel comprehension of the pathophysiology of -thalassemia, iron chelation therapy still remains the most efficacious approach for reducing the morbidity and mortality associated with iron overload in patients with NTDT and TDT (118)

For 1 mg this equals 0.1 ml or 10 units on the syringe scale

Lipoxygenases and phosphorylase kinase G2 are two key drivers of lipid peroxidation (Yang et al., 2016), which can directly damage phospholipids and intrigue ferroptosis