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As in RCT, participants were mostly adults (mean age 30.455.5 years) and females (6095%) with class II obesity, except for studies conducted in China and South Korea, enrolling patients with a mean BMI ranging from 30.8 to 33 kg/m 2 53,54,62,66

Reconstitute: Add 3.0 mL bacteriostatic water ~ 3.33 mg/mL concentration

Use the conservative rule: reconstitute only what is needed, refrigerate at 2-8 C, protect from light, label the date, and discard around 28 days or sooner if the solution changes appearance or sterility is compromised

Massage onto skin and allow to rest 1 to 2 minutes before rinsing

Product presentation, claims, intended use and surrounding circumstances all matter