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Description

Tesofensine is used to achieve medical weight loss in obese and overweight patients

Glutathione (oxidized glutathione, GSSG) molecule

However, it can be depleted by age, health concerns, or other factors

In the acute phase, the neuroinflammatory response worsens BBB injury by degrading tight junctions and the extracellular matrix, promoting neuroglial proliferation, and activating cardiomyocytes, thereby further increasing its permeability